产品目录

分子量：Approximately 5.4kDa,a single non-glycosylated polypeptide chain containing 50 amino acids.
储存条件：冷冻（-20℃）

概述

B-Cell Maturation Antigen(BCMA),encoded by the TNFRSF17 gene in humans.It is a member of the TNF receptor superfamily and a type III membrane protein containing one extracellular cysteine rich domain.It is expressed on mature B-cells and other B-cell lines.BCMA can binds to TNFSF13B/BLyS/BAFF and TNFSF13/APRIL,and has functions that promotes B-cell survival,plays a role in the regulation of humoral immunity,and activates NF-kappa-B and JNK BCMA.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞98%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated murine B cells is no less than 40ng/ml,corresponding to a specific activity of>2.5×104 IU/mg in the presence of 100 ng/ml human APRIL.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 30%acetonitrile,0.1%TFA.
内毒素	Less than 1 EU/μg of rHuBCMA as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA

相关搜索：重组人BCMA，BCMA, Human，Recombinant Human B-Cell Maturation Antigen